Endometrial Cancer (2024)

Abnormal Uterine Bleeding: Bleeding from the uterus that is different from what is normal for a woman who is not pregnant. This bleeding may vary in how long, how regular, and how often it occurs.

Anesthesia: Relief of pain by loss of sensation.

Body Mass Index (BMI): A number calculated from height and weight. BMI is used to determine whether a person is underweight, normal weight, overweight, or obese.

Chemotherapy: Treatment of cancer with drugs.

Dilation and Curettage (D&C): A procedure that opens the cervix so tissue in the uterus can be removed using an instrument called a curette.

Endometrial Biopsy: A procedure in which a small amount of the tissue lining the uterus is removed and examined under a microscope.

Endometrial Cancer: Cancer of the lining of the uterus.

Endometrial Intraepithelial Neoplasia (EIN): A precancerous condition in which areas of the lining of the uterus grow too thick.

Endometrium: The lining of the uterus.

Estrogen: A female hormone produced in the ovaries.

Fallopian Tubes: Tubes through which an egg travels from the ovary to the uterus.

Gene: A segment of DNA that contains instructions for the development of a person’s physical traits and control of the processes in the body. The gene is the basic unit of heredity and can be passed from parent to child.

Gynecologic Oncologist: A doctor with special training and experience in the diagnosis and treatment of cancer of the female reproductive organs.

Hormone Therapy: Treatment in which estrogen and often progestin are taken to help relieve symptoms that may happen around the time of menopause.

Hysterectomy: Surgery to remove the uterus.

Hysteroscope: A thin, lighted telescope that is used to look inside the uterus and do procedures.

In Vitro Fertilization (IVF): A procedure in which an egg is removed from a woman’s ovary, fertilized in a laboratory with the man’s sperm, and then transferred to the woman’s uterus to achieve a pregnancy.

Lymph Nodes: Small groups of special tissue that carry lymph, a liquid that bathes body cells. Lymph nodes are connected to each other by lymph vessels. Together, these make up the lymphatic system.

Lynch Syndrome: Genetic condition that increases a person’s risk of cancer of the colon, rectum, ovary, uterus, pancreas, and bile duct.

Menopause: The time when a woman’s menstrual periods stop permanently. Menopause is confirmed after 1 year of no periods.

Metastasize: Spreading of cancer to other parts of the body.

Mutation: A change in a gene that can be passed from parent to child.

Obstetrician–Gynecologist (Ob-Gyn): A doctor with special training and education in women’s health.

Ovaries: Organs in women that contain the eggs necessary to get pregnant and make important hormones, such as estrogen, progesterone, and testosterone.

Perimenopause: The time period leading up to menopause.

Polycystic Ovary Syndrome (PCOS): A condition that leads to a hormone imbalance that affects a woman’s monthly menstrual periods, ovulation, ability to get pregnant, and metabolism.

Progesterone: A female hormone that is made in the ovaries and prepares the lining of the uterus for pregnancy.

Progestin: A synthetic form of progesterone that is similar to the hormone made naturally by the body.

Radiation Therapy: Treatment with radiation.

Recurrence: The return of disease or its signs and symptoms.

Salpingo-oophorectomy: Surgery to remove an ovary and fallopian tube.

Stage: Stage can refer to the size of a tumor and the extent (if any) to which the disease has spread.

Transvagin*l Ultrasound Exam: A type of ultrasound in which the device is placed in your vagin*.

Tumor: A growth or lump made up of cells.

Uterus: A muscular organ in the female pelvis. During pregnancy, this organ holds and nourishes the fetus.

Endometrial Cancer (2024)

FAQs

What is the life expectancy of someone with endometrial cancer? ›

Survival rates by age
Age5-year survival rate
15–3990.8%
40–6485.1%
65–7478.3%
75 and over68%
Feb 1, 2023

What were your first signs of endometrial cancer? ›

Unusual vagin*l bleeding, spotting, or other discharge

About 90% of women with endometrial cancer have abnormal vagin*l bleeding. This might be a change in their periods, bleeding between periods, or bleeding after menopause. Non-cancer problems can also cause abnormal bleeding.

What is the #1 risk factor for endometrial cancer? ›

The major risk factor for endometrial carcinoma (EC) is the presence of a clinical scenario associated with an excess of endogenous or exogenous estrogen without adequate opposition by a progestin.

How do you beat endometrial cancer? ›

It will usually include surgery, chemotherapy or radiotherapy. It may also include treatment with targeted medicines to treat the cancer.

Will a hysterectomy cure endometrial cancer? ›

Surgery is often the main treatment for endometrial cancer and consists of a hysterectomy, often along with a salpingo-oophorectomy, and removal of lymph nodes. In some cases, pelvic washings are done, the omentum is removed, and/or peritoneal biopsies are done.

What are the odds of beating endometrial cancer? ›

5-year relative survival rates for endometrial cancer
SEER* Stage5-year Relative Survival Rate
Localized95%
Regional70%
Distant18%
All SEER stages combined81%
Jan 17, 2024

What are the red flags of endometrial cancer? ›

Endometrial/uterine/womb cancer: bleeding in between periods, after sex or after the menopause. heavier periods. abnormal vagin*l discharge.

What stage is endometrial cancer usually found? ›

Stage 1A: This means the cancer is in the inner lining of your uterus, called the endometrium. It may have spread less than halfway into the underlying muscle.

Can you have endometrial cancer for years and not know it? ›

Approximately 15 to 20% of women with endometrial cancer may not have any symptoms. Symptoms that do occur may include: Unusual bleeding. Abdominal cramps, which are caused when the tumor blocks the cervical canal and keeps the blood from being expelled.

Where is the first place endometrial cancer spreads? ›

Endometrial cancer typically grows from the endometrium (the inside of the uterus) into the surrounding muscle layer (the myometrium) towards the outer lining of the uterus. It can also grow into the adjacent fallopian tubes, which are attached to the uterus and from here to the ovaries.

What should I avoid if I have endometrial cancer? ›

What foods should you avoid for uterine cancer?
  • Dairy products.
  • Meat.
  • Saturated fats.
  • Foods and drinks high in calories, sodium and/or sugar.

What is the root cause of endometrial cancer? ›

The cause of endometrial cancer isn't known. What's known is that something happens to cells in the lining of the uterus that changes them into cancer cells. Endometrial cancer starts when cells in the lining of the uterus, called the endometrium, get changes in their DNA.

What feeds endometrial cancer? ›

As with many cancers, the risk for uterine cancers appears to be associated with greater intakes of foods found in Western diets (animal products, refined carbohydrates). [22],[23] Risk may be lower among women whose diets are high in fruits, vegetables, whole grains, and legumes.

Is endometrial cancer 100% curable? ›

Outlook / Prognosis

The five-year survival rate for endometrial cancer is 81%. That means 81% of people diagnosed with the disease are alive five years later. The rate is even higher when cancer hasn't spread outside your uterus. Then, the survival rate reaches as high as 95%.

What kills endometrial cancer? ›

Endometrial cancer is usually first treated with surgery to remove the cancer. This may include removing the uterus, fallopian tubes and ovaries. Other treatment options may include radiation therapy or treatments using medicines to kill the cancer cells.

Does endometrial cancer spread quickly? ›

The most common type of endometrial cancer (type 1) grows slowly. It most often is found only inside the uterus. Type 2 is less common. It grows more quickly and often spreads to other parts of the body.

What are the end stages of endometrial cancer? ›

Stage IV cancers

Stage IVA: These endometrial cancers have grown into the bladder or bowel. Stage IVB: These endometrial cancers have spread to lymph nodes outside the pelvis or para-aortic area. This stage also includes cancers that have spread to the liver, lungs, omentum, or other organs.

What is the leading cause of death among endometrial cancer survivors? ›

Cardiovascular disease is the leading cause of death among endometrial cancer survivors.

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