Cortisone Shots: How They Work and Side Effects (2024)

What happens when I get a cortisone shot?

A healthcare provider may give you a cortisone shot during a normal office visit. Or they might schedule a separate visit for the injection.

Your provider will insert a needle into the area that needs treated and inject cortisone (a steroid). They might use an ultrasound to guide the injection needle.

Do cortisone shots hurt?

A cortisone shot might sting when your provider puts the needle into your skin, but it shouldn’t cause intense pain. Your provider might give you a local anesthetic to numb the area around the injection site.

Tell your provider if you experience fear or anxiety about getting shots. They’ll help you relax and feel more comfortable about receiving a steroid injection.

What does a cortisone shot do?

A cortisone shot reduces pain and inflammation in the area around where your provider injects it.

Inflammation usually happens when your immune system sends cells to fight infections or heal an injury in your body. Your provider will inject cortisone into the part of your body that’s experiencing inflammation. The cortisone calms your immune system’s response in that location. This reduces pain and inflammation.

Does a cortisone shot affect the whole body?

Your provider will inject cortisone directly into the area of your body that’s experiencing inflammation. This will deliver the dose of corticosteroid right where it’s needed.

The steroid medication will circulate through your bloodstream and can affect other areas of your body. But these systemic effects are usually so small that you won’t notice them.

Cortisone Shots: How They Work and Side Effects (2024)

FAQs

What is the downside of getting cortisone shots? ›

Cortisone shots commonly cause a short-term flare in pain, swelling and irritation for up to two days after the injection. After that, the pain, swelling and irritation should generally lessen. The pain relief can last up to several months.

Why do doctors not like to give cortisone shots? ›

As Dr. Cunningham explains: “Most orthopedic surgeons don't like to give cortisone shots repetitively because, while it's good to relieve inflammation and pain, it can also lead to degenerative changes of the cartilage lining the joint.” Doctors usually won't give a patient more than three to four shots per year.

What happens to your body when you get a cortisone shot? ›

Cortisone works by decreasing the inflammatory response in the joint, muscle or other part of the body in which it is being injected. Typically, whenever there is inflammation, there is also a significant pain response. Therefore, if we can decrease the inflammation, we can usually decrease some of the pain.

What should you not do after a cortisone shot? ›

But try to avoid overexerting your back or doing any high-impact activities (such as running) for a week after your procedure. You may be advised to rest for longer if: You experience moderate cortisone side effects, such as cortisone flare or swelling around the joint.

What is the alternative to cortisone shots? ›

PRP therapy is a relatively new treatment method that uses the body's natural healing properties to treat joint pain. By injecting platelet-rich plasma directly into the affected joint, doctors are able to reduce pain and improve joint function.

What is the downfall of a cortisone shot? ›

It's rare for steroid injections to cause severe side effects, but it's possible to experience: Infections at the injection site. High blood pressure (hypertension). Fluid retention and increased swelling.

What not to mix with cortisone? ›

Some medicines that corticosteroids could interact with include:
  • anticoagulant medicines like warfarin.
  • anticonvulsants – used to prevent seizures (fits)
  • diabetes medication.
  • HIV medication.
  • some vaccinations.
  • non-steroidal anti-inflammatory drugs (NSAIDs)
May 31, 2024

Are cortisone shots bad for your heart? ›

When injected, cortisone affects your body's balance of water and electrolytes. That can cause fluid retention and lead to elevated blood pressure, increasing your risk of heart complications like heart failure or stroke.

Who shouldn't have cortisone injections? ›

Your doctor won't inject steroids if there's an infection in the inflamed area or another part of your body. If a joint is severely damaged, injections probably won't help. If you have a bleeding problem or are taking anticoagulant medications (often called blood thinners), steroid injections may cause bleeding.

Why no bath after cortisone shot? ›

Avoiding submerging the injection site: Submerging your injection site can introduce bacteria, leaving you vulnerable to infection. You can shower, but it's best to avoid baths, hot tubs and swimming pools until your injection site has healed.

Is walking good after a cortisone injection? ›

After a cortisone injection, it is strongly advised to rest the affected joint for 24 hours and refrain from doing strenuous activity or exercise for several days. Resting after the injection is vital to reduce inflammation effectively.

Why does a cortisone shot hurt so much? ›

The corticosteroids in the injection are formulated as slow-release crystals to give you long-term pain relief. Pain relief usually lasts for several months. However, the presence of these crystals can irritate your joint, which is what creates the sensation of pain around the area of the shot.

What foods should you avoid after a cortisone shot? ›

It is important to avoid "simple" carbohydrates and concentrated sweets, such as cakes, pies, cookies, jams, honey, chips, breads, candy and other highly processed foods. This helps keep blood sugar low. Limit saturated fat and cholesterol. Choose lean meats, poultry and fish.

How many days should you rest after a cortisone shot? ›

After any injection, whether it is Hyaluronic acid (HA), Platelet Rich Plasma (PRP) or steroid (cortisone) we recommend you rest for a minimum of 2 days. This is to allow your body to adapt to what we have injected. Occasionally, some people will have a flare after an injection.

Why can you only have three cortisone shots in a lifetime? ›

Getting too many cortisone shots can cause serious problems like damaged cartilage and bone death. It can also make it harder to manage other conditions such as diabetes.

Are cortisone injections worth having? ›

If successful, an injection can relieve pain for several weeks or even several months, but keep in mind that results vary widely. Your pain may not be relieved at all, or it may go away and never come back. Doctors are not sure why results vary and who will respond best.

Can steroid injections do more harm than good? ›

Steroid injections can stop the body producing natural hormones, which can be dangerous if you get ill, have an accident or need an operation. There is evidence that this can be a risk for up to one month after just one steroid injection.

What are the long term side effects of cortisone? ›

Long-term corticosteroid use may be associated with more serious sequel, including osteoporosis, aseptic joint necrosis, adrenal insufficiency, gastrointestinal, hepatic, and ophthalmologic effects, hyperlipidemia, growth suppression, and possible congenital malformations.

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